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        "abstract": "The inflatable habitat described in this paper is a horizontally-oriented cylindrical pneumatic structure. It is part of NASA's ongoing effort to study inflatables as alternative habitats for the Space Exploration Initiative. This inflatable habitat provides a living and working environment for a crew of 12. It is an 8-m diameter by 45.34-m cylinder containing 2145 cu m of volume. Two levels of living and working areas make up the 547 sq m of floor space.",
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        "title": "Brain-Pituitary Axis Development In The CEBAS Minimodule",
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        "topic": "reproduction-genetics",
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        "authors": [
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        "abstract": "The CEBAS minimodule system is a man-made aquatic ecological system that incorporates animals, plants, snails, and microorganisms. It has been proposed that CEBAS will lead to a multigenerational experimental facility for utilization in a space station as well as for the development of an aquatic CELSS to produce animal and plant biomass for human nutrition. In this context, research on the reproductive biology of the organisms within the system should receive the highest priority. 1bus, the goals of our proposal were to provide information on space-flight-induced changes in the brain-pituitary axis and in the organs that receive information from the environment in the vertebrate selected for the CEBAS Minimodule program, the freshwater teleost Xiphophorus helleri (the swordtail). We studied the development of the brain- pituitary axis in neonates, immature and mature swordtails using histology, cytology, immunohistochemistry, morphometry, and in situ histochemistry to evaluate the synthesis, storage, and release of neurotransmitters, neuroregulatory peptides, neurohormones, and pituitary hormones as well as the structure of the organs and cells that produce, store, or are the target organs for these substances. We flew experiments in the CEBAS-minimodule on two shuttle missions, STS-89 and STS-90. In both flights four gravid females and about 200 juvenile (7 days old) swordtails (Xiphophorus helleri) constituted the aquatic vertebrates to be studied, in addition to the plants and snails that were studied by other team members. In a sample sharing agreement developed with Dr. Volker Bluem, organizer of the CEBAS research program, we received a small number of the juveniles and shared the brains of two adult females.",
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        "selectionNote": "Curated for CEBAS investigations linking aquatic closed-ecosystem operation with vertebrate brain-pituitary responses, combining habitat ecology and organism health.",
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        "authors": [
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        "abstract": "NASA is actively conducting advanced propulsion research and technology development in various in-space transportation technologies with potential application to interstellar missions and precursors. Within the last few years, interest in the scientific community in interstellar missions as well as outer heliospheric missions, which could function as interstellar precursor missions, has increased. A mission definition team was charted by NASA to define such a precursor, The Interstellar Probe, which resulted in a prioritization of relatively near-term transportation technologies to support its potential implementation. In addition, the goal of finding and ultimately imaging extra solar planets has raised the issue of our complete inability to mount an expedition to such as planet, should one be found. Even contemplating such a mission with today's technology is a stretch of the imagination. However, there are several propulsion concepts, based on known physics, that have promise to enable interstellar exploration in the future. NASA is making small, incremental investments in some key advanced propulsion technologies in an effort to advance their state-of-the-art in support potential future mission needs. These technologies, and their relative maturity, are described.",
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        "selectionNote": "Curated as a snapshot of NASA advanced-propulsion work connecting outer-heliospheric precursors with longer-term interstellar mission concepts and technology prioritization.",
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        "title": "Mammalian development in space",
        "url": "https://ntrs.nasa.gov/citations/20040087475",
        "topic": "reproduction-genetics",
        "year": 2003,
        "publishedAt": "2003-01-01T00:00:00.0000000+00:00",
        "authors": [
          "Ronca, April E."
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        "abstract": "Life on Earth, and thus the reproductive and ontogenetic processes of all extant species and their ancestors, evolved under the constant influence of the Earth's l g gravitational field. These considerations raise important questions about the ability of mammals to reproduce and develop in space. In this chapter, I review the current state of our knowledge of spaceflight effects on developing mammals. Recent studies are revealing the first insights into how the space environment affects critical phases of mammalian reproduction and development, viz., those events surrounding fertilization, embryogenesis, pregnancy, birth, postnatal maturation and parental care. This review emphasizes fetal and early postnatal life, the developmental epochs for which the greatest amounts of mammalian spaceflight data have been amassed. The maternal-offspring system, the coordinated aggregate of mother and young comprising mammalian development, is of primary importance during these early, formative developmental phases. The existing research supports the view that biologically meaningful interactions between mothers and offspring are changed in the weightlessness of space. These changes may, in turn, cloud interpretations of spaceflight effects on developing offspring. Whereas studies of mid-pregnant rats in space have been extraordinarily successful, studies of young rat litters launched at 9 days of postnatal age or earlier, have been encumbered with problems related to the design of in-flight caging and compromised maternal-offspring interactions. Possibilities for mammalian birth in space, an event that has not yet transpired, are considered. In the aggregate, the results indicate a strong need for new studies of mammalian reproduction and development in space. Habitat development and systematic ground-based testing are important prerequisites to future research with young postnatal rodents in space. Together, the findings support the view that the environment within which young mammals develop, comprised of its mother and siblings, is of paramount importance in interpreting spaceflight effects.",
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        "selectionNote": "Curated for experimental questions around mammalian development under spaceflight conditions, a high-consequence gap for any genuinely multigenerational habitat.",
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        "evidenceBoundary": "NTRS metadata and abstract provide research context, but this pass did not validate study design, reproductive outcomes, welfare, or human applicability. It is high-consequence biology context, not reproductive or medical guidance."
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      "snapshot": {
        "id": "ntrs-20040089359",
        "title": "The Voyager Interstellar Mission",
        "url": "https://ntrs.nasa.gov/citations/20040089359",
        "topic": "mission-architecture",
        "year": 1997,
        "publishedAt": "1997-01-01T00:00:00.0000000+00:00",
        "authors": [
          "Rudd, R. P.",
          "Hall, J. C.",
          "Spradlin, G. L."
        ],
        "publisher": "Legacy CDMS",
        "resourceType": "Reprint (Version printed in journal)",
        "access": "open metadata",
        "abstract": "The Voyager Interstellar Mission began on January 1, 1990, with the primary objective being to characterize the interplanetary medium beyond Neptune and to search for the transition region between the interplanetary medium and the interstellar medium. At the start of this mission, the two Voyager spacecraft had already been in flight for over twelve years, having successfully returned a wealth of scientific information about the planetary systems of Jupiter, Saturn, Uranus, and Neptune, and the interplanetary medium between Earth and Neptune. The two spacecraft have the potential to continue returning science data until around the year 2020. With this extended operating lifetime, there is a high likelihood of one of the two spacecraft penetrating the termination shock and possibly the heliopause boundary, and entering interstellar space before that time. This paper describes the Voyager Interstellar Mission--the mission objectives, the spacecraft and science payload, the mission operations system used to support operations, and the mission operations strategy being used to maximize science data return even in the event of certain potential spacecraft subsystem failures. The implementation of automated analysis tools to offset and enable reduced flight team staffing levels is also discussed.",
        "keywords": [
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          "long duration",
          "Voyager Project",
          "unmanned",
          "Solar System",
          "Space Flight/instrumentation",
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          "Telecommunications",
          "Support, U.S. Gov't, Non-P.H.S",
          "Computer Systems",
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          "Research Design",
          "Planets"
        ],
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        "selectionNote": "Curated for Voyager Interstellar Mission objectives, aging-spacecraft operations, science-payload management, communications, and long-duration mission design.",
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      "recordId": "ntrs-20170009104",
      "title": "Benefits of International Collaboration on the International Space Station",
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        "id": "ntrs-20170009104",
        "title": "Benefits of International Collaboration on the International Space Station",
        "url": "https://ntrs.nasa.gov/citations/20170009104",
        "topic": "institutions-workforce",
        "year": 2017,
        "publishedAt": "2017-09-25T00:00:00.0000000+00:00",
        "authors": [
          "Hasbrook, Pete",
          "Robinson, Julie A.",
          "Brown Tate, Judy",
          "Thumm, Tracy",
          "Cohen, Luchino",
          "Marcil, Isabelle",
          "De Parolis, Lina",
          "Hatton, Jason"
        ],
        "publisher": "Johnson Space Center",
        "resourceType": "Conference Paper",
        "access": "open full text",
        "abstract": "The International Space Station is a valuable platform for research in space, but the benefits are limited if research is only conducted by individual countries. Through the efforts of the ISS Program Science Forum, international science working groups, and interagency cooperation, international collaboration on the ISS has expanded as ISS utilization has matured. Members of science teams benefit from working with counterparts in other countries. Scientists and institutions bring years of experience and specialized expertise to collaborative investigations, leading to new perspectives and approaches to scientific challenges. Combining new ideas and historical results brings synergy and improved peer-reviewed scientific methods and results. World-class research facilities can be expensive and logistically complicated, jeopardizing their full utilization. Experiments that would be prohibitively expensive for a single country can be achieved through contributions of resources from two or more countries, such as crew time, up- and downmass, and experiment hardware. Cooperation also avoids duplication of experiments and hardware among agencies. Biomedical experiments can be completed earlier if astronauts or cosmonauts from multiple agencies participate. Countries responding to natural disasters benefit from ISS imagery assets, even if the country has no space agency of its own. Students around the world participate in ISS educational opportunities, and work with students in other countries, through open curriculum packages and through international competitions. Even experiments conducted by a single country can benefit scientists around the world, through specimen sharing programs and publicly accessible \"open data\" repositories. For ISS data, these repositories include GeneLab and the Physical Science Informatics System. Scientists can conduct new research using ISS data without having to launch and execute their own experiments. Multilateral collections of research results publications, maintained by the ISS international partnership and accessible via nasa.gov, make ISS results available worldwide, and encourage new users, ideas and research. The paper explores international collaboration history, its evolution and maturation, change of focus during its different phases, and growth of its effectiveness (in accordance with the especially established criteria) in the light of benefits for the entire ISS community. With the International Space Station extended through at least 2024, more crew time becoming available and new facilities arriving on board the ISS, these benefits of international scientific collaboration on the ISS can only increase.",
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      "recordId": "ntrs-20180004338",
      "title": "Human Space Flight and Future Major Space Astrophysics Missions: Servicing and Assembly",
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        "id": "ntrs-20180004338",
        "title": "Human Space Flight and Future Major Space Astrophysics Missions: Servicing and Assembly",
        "url": "https://ntrs.nasa.gov/citations/20180004338",
        "topic": "assembly-logistics",
        "year": 2017,
        "publishedAt": "2017-09-05T04:00:00.0000000+00:00",
        "authors": [
          "Harley Thronson",
          "Bradley M. Peterson",
          "Matthew Greenhouse",
          "Howard MacEwen",
          "Rudranarayan Mukherjee",
          "Ronald Polidan",
          "Benjamin Reed",
          "Nicholas Siegler"
        ],
        "publisher": "SPIE",
        "resourceType": "Accepted Manuscript (Version with final changes)",
        "access": "open full text",
        "abstract": "Some concepts for candidate future \"flagship\" space observatories approach the payload limits of the largest launch vehicles planned for the next few decades, specifically in the available volume in the vehicle fairing. This indicates that an alternative to autonomous self-deployment similar to that of the James Webb Space Telescope will eventually be required. Moreover, even before this size limit is reached, there will be significant motivation to service, repair, and upgrade in-space missions of all sizes, whether to extend the life of expensive facilities or to replace outworn or obsolete onboard systems as was demonstrated so effectively by the Hubble Space Telescope program. In parallel with these challenges to future major space astronomy missions, the capabilities of in-space robotic systems and the goals for human space flight in the 2020s and 2030s offer opportunities for achieving the most exciting science goals of the early 21st Century. In this paper, we summarize the history of concepts for human operations beyond the immediate vicinity of the Earth, the importance of very large apertures for scientific discovery, and current capabilities and future developments in robot- and astronaut-enabled servicing and assembly.",
        "keywords": [
          "Hubble Space Telescope",
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      "recordId": "ntrs-20190000915",
      "title": "Mach Effects for in Space Propulsion: Interstellar Mission",
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        "id": "ntrs-20190000915",
        "title": "Mach Effects for in Space Propulsion: Interstellar Mission",
        "url": "https://ntrs.nasa.gov/citations/20190000915",
        "topic": "mission-architecture",
        "year": 2018,
        "publishedAt": "2018-02-01T05:00:00.0000000+00:00",
        "authors": [
          "Heidi Fearn",
          "Gary C Hudson",
          "Marshall Eubanks",
          "Bruce Long",
          "Jose Rodal",
          "Paul March",
          "James F Woodward",
          "Nolan Van Rossum"
        ],
        "publisher": "Headquarters",
        "resourceType": "Contractor or Grantee Report",
        "access": "open full text",
        "abstract": "To explore the feasibility of building a Mach Effect propulsion system capable of reaching Proxima Centauri, with a close encounter of Proxima b, in significantly less than a human lifetime (20-25 yrs.) and to conceptualize an interstellar probe using the Mach Effect propulsion method. To gather data and send back to Earth, within the 25 year mission duration.",
        "keywords": [
          "Interstellar",
          "Mach Effect",
          "Propulsion"
        ],
        "sourceClass": "editor-selected-context",
        "selectionNote": "Curated as a bounded NIAC-era Mach-effect interstellar-probe concept addressing a Proxima mission, useful for mapping extraordinary propulsion proposals and their stated test objectives.",
        "verifiedAt": "2026-07-25",
        "curationTopic": "speculative propulsion",
        "evidenceBoundary": "NTRS lists open full text, but a contractor feasibility study is not experimental validation of Mach-effect thrust, an interstellar trajectory, or a 25-year return. It is low-readiness context, not evidence for feasibility or a GShips claim."
      }
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    {
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      "recordId": "ntrs-20210001153",
      "title": "Intelligent Mobile Systems for Assembly, Maintenance and Operations for Space Solar Power",
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        "title": "Intelligent Mobile Systems for Assembly, Maintenance and Operations for Space Solar Power",
        "url": "https://ntrs.nasa.gov/citations/20210001153",
        "topic": "power-thermal",
        "year": 1999,
        "publishedAt": "1999-02-27T00:00:00.0000000+00:00",
        "authors": [
          "Ganino, T.",
          "Kennedy, B.",
          "Hickey, G."
        ],
        "publisher": "Jet Propulsion Laboratory",
        "resourceType": "Other",
        "access": "open metadata",
        "abstract": "NASA has been commissioned to investigate the feasibility of an orbiting Space Solar Power system that is capable of generating power from space and transmitting the power to earth based rectennas.",
        "keywords": [
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          "solar",
          "power",
          "robotics",
          "autonomous",
          "assembly",
          "reconfigurable",
          "systems"
        ],
        "sourceClass": "editor-selected-context",
        "selectionNote": "Curated for an early intelligent-mobile-systems concept linking robotic assembly, maintenance, operations, and reconfiguration to very large orbital solar-power infrastructure.",
        "verifiedAt": "2026-07-25",
        "curationTopic": "autonomous assembly and maintenance",
        "evidenceBoundary": "Only NTRS metadata and a short abstract are open here; feasibility, autonomy performance, economics, and the space-solar-power premise were not validated. It is historical precursor context, not claim evidence."
      }
    },
    {
      "recordType": "atlas-resource",
      "recordId": "ntrs-20210017840",
      "title": "Quasi-Wireless Capacitive Power Transfer with Secure Data Acquisition for Robotic Systems in Space Infrastructure",
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      "snapshot": {
        "id": "ntrs-20210017840",
        "title": "Quasi-Wireless Capacitive Power Transfer with Secure Data Acquisition for Robotic Systems in Space Infrastructure",
        "url": "https://ntrs.nasa.gov/citations/20210017840",
        "topic": "cybersecurity",
        "year": 2021,
        "publishedAt": "2021-10-12T05:00:00.0000000+00:00",
        "authors": [
          "T Burks",
          "G Cathey",
          "V Kholodilo",
          "D Ulybyshev",
          "B Northern",
          "M Gupta",
          "M Pearce",
          "T Marcrum"
        ],
        "publisher": "Marshall Space Flight Center",
        "resourceType": "Conference Paper",
        "access": "open full text",
        "abstract": "Space exploration is dependent on robotic systems\nthat utilize end-effectors to collect samples, probe surfaces, and\nmanipulate objects. These systems can rarely be designed to\ndo all three, forcing engineers to make tradeoffs based on the\nmission parameters - i.e. should the robotic appendage have a\nclaw, drill, or shovel, and which would be best suited for the\nmission? Additionally, as more industrial and government entities\npartake in space exploration, data protection is needed in transit\nand at rest. To address these challenges, we present a first-of-its-\nkind robotic linkage that has no wiring between the joints.\nInstead, quasi-wireless capacitive (QWiC) power transfer is used\nto send energy over the robot’s chassis without a return wire.\nThis enables the system to be completely modular through the\nuse of single-contact permanent magnet connections, allowing\nrapid alterations in joint kinematics and/or the changing of end-effectors.\nFor collecting sensor data from the robotic arm and to send\nremote commands to it, we use a Supervisory Control and Data\nAcquisition (SCADA) system. Data transmission relies on MQTT\nand OPC UA communication protocols with encryption. The\nSCADA server logs and archives sensor data and provides the\nfunctionality for authorized users to send remote commands\nfrom SCADA client(s) to motors. A SCADA client can be any\nof the web browsers that connects to a server via a secure\ncommunication channel using SSL protocol. Furthermore, as an\nextra data protection mechanism, we inject noise to the sensor\ndata traffic, which obfuscates the timing of sensor data packets\nand adds confusion about which data packet represents which\nmotor.",
        "keywords": [
          "wireless sensor networks",
          "IoT",
          "space cybersecurity",
          "SCADA systems",
          "wireless power"
        ],
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        "selectionNote": "Curated because “Quasi-Wireless Capacitive Power Transfer with Secure Data Acquisition for Robotic Systems in Space Infrastructure” covers wireless sensor networks, IoT, space cybersecurity, SCADA systems; it materially informs GShips work on secure space robotics.",
        "verifiedAt": "2026-07-25",
        "curationTopic": "secure-space-robotics",
        "evidenceBoundary": "NTRS provides open full text, but this conference paper was screened for curation rather than independently or domain reviewed; inclusion is contextual, not automatic claim evidence."
      }
    },
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      "recordId": "ntrs-20240002605",
      "title": "RadLab: A Comprehensive Database and Analysis Toolkit for Space Radiation Measurements Relevant to Space Radiation Biology",
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      "recordFingerprint": "57ee4c9c0d2502dc7d6f85eb3cc21cd659a198fc9c0f887f084d56ffe2d92806",
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      "snapshot": {
        "id": "ntrs-20240002605",
        "title": "RadLab: A Comprehensive Database and Analysis Toolkit for Space Radiation Measurements Relevant to Space Radiation Biology",
        "url": "https://ntrs.nasa.gov/citations/20240002605",
        "topic": "radiation-environment",
        "year": 2024,
        "publishedAt": "2024-05-01T04:00:00.0000000+00:00",
        "authors": [
          "Kirill Grigorev",
          "Ana Eveina Uriarte Acuna",
          "Lauren Marie Sanders",
          "Danielle Kristine Lopez",
          "Ryan Thomas Scott",
          "Samrawit Getachew Gebre",
          "Jack Miller",
          "Livio Narici"
        ],
        "publisher": "Ames Research Center",
        "resourceType": "Conference Paper",
        "access": "open metadata",
        "abstract": "RadLab, a new addition to the NASA Open Science Data Repository (OSDR), is a public platform for space radiation data relevant to human space exploration. RadLab consists of a database, a submission portal, and user-friendly visualization and data analysis tools, including a graphical user interface (GUI) and an application programming interface (API). \n\nInvestigators from ISS partners including Germany, Italy, Canada, Hungary, the Czech Republic, Russia, Japan have committed to providing data from their instruments. RadLab will also include data from other spacecraft in LEO: the Space Shuttle, the Mir space station, biosatellites; and beyond LEO: the lunar and the Martian surface, the heliocentric orbit at 1 AU, Mars orbit, and Earth-Mars space. \n\nOnce fully operational, RadLab will provide open, centralized access to space radiation physics data relevant to human space exploration; a platform for submission of data by agencies and research institutions responsible for radiation detectors deployed in space; analysis tools to facilitate detector and dataset intercomparison to better understand space habitat radiation environments; capabilities for space biology investigators to determine the radiation environment to which samples were exposed.\n\nA RadLab Working Group (RLWG) has been formed, modeled on the GeneLab Analysis Working Groups and comprised of data contributors and users. RLWG tasks include identifying data sources, normalizing data from diverse detectors, expanding the analysis toolkit and, perhaps most importantly, sharing ideas for research exploiting capabilities of RadLab.\n\nWe will provide an overview of RadLab data and capabilities and discuss examples of its potential as a resource for open science.",
        "keywords": [
          "radiation",
          "ISS",
          "API",
          "visualization",
          "web application"
        ],
        "sourceClass": "editor-selected-context",
        "selectionNote": "Curated for RadLab, a database and toolkit intended to make space-radiation measurements discoverable and usable across instrument, environment, and mission analyses.",
        "verifiedAt": "2026-07-25",
        "curationTopic": "radiation data infrastructure",
        "evidenceBoundary": "The NTRS record describes the platform, but this pass did not audit dataset completeness, calibration, software behavior, or continued availability. It is infrastructure context, not direct claim evidence."
      }
    },
    {
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      "recordId": "ntrs-20240007078",
      "title": "Advances in High-rate Delay Tolerant Networking On-board the International Space Station",
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      "snapshot": {
        "id": "ntrs-20240007078",
        "title": "Advances in High-rate Delay Tolerant Networking On-board the International Space Station",
        "url": "https://ntrs.nasa.gov/citations/20240007078",
        "topic": "communications-navigation",
        "year": 2024,
        "publishedAt": "2024-07-19T04:00:00.0000000+00:00",
        "authors": [
          "Rachel Dudukovich",
          "Daniel Raible",
          "Brian Tomko",
          "Nadia Kortas",
          "Ethan Schweinsberg",
          "Thomas Basciano",
          "William Pohlchuck",
          "Joshua Deaton"
        ],
        "publisher": "Glenn Research Center",
        "resourceType": "Conference Paper",
        "access": "open full text",
        "abstract": "The High-rate Delay Tolerant Networking (HDTN) project at the NASA John H. Glenn Research Center (GRC) is developing a performance optimized Delay Tolerant Networking\n(DTN) implementation which is able to provide reliable multigigabit\nper second automated network communications for near-Earth and deep space missions. To that end, this paper provides an overview of the testing and integration efforts culminating in a high-rate DTN demonstration onboard the International\nSpace Station (ISS). Over several years, the HDTN team has performed a series of end-to-end tests between the Software Development and Integration Laboratory (SDIL) at the Lyndon B. Johnson Space Center (JSC) and Marshall Space Flight Center’s Huntsville Operations Support Center (HOSC). The testing has focused on a realistic emulation of the ISS Ku-band RF link, which operates at a maximum of 500 Mbps downlink with a 600 ms round-trip time. In this environment, the HDTN onboard gateway has been tested for interoperability with ISS payload nodes and the DTN ground gateway, store and forward capability, reliable transport using the Licklider Transmission Protocol (LTP), and successful recovery from unexpected loss of signal. In addition to integration testing, HDTN has developed a series of software engineering practices to ensure the stability\nand maturity of the implementation. As the result, HDTN has successfully demonstrated high-rate DTN services onboard the ISS. This paper concludes with a summary of preliminary flight testing results from the Integrated LCRD LEO User Modem and\nAmplifier Terminal networking experiments.",
        "keywords": [
          "Delay tolerant networking",
          "optical communication,",
          "International Space Station"
        ],
        "sourceClass": "editor-selected-context",
        "selectionNote": "Curated because “Advances in High-rate Delay Tolerant Networking On-board the International Space Station” covers Delay tolerant networking, optical communication,, International Space Station; it materially informs GShips work on delay tolerant networking.",
        "verifiedAt": "2026-07-25",
        "curationTopic": "delay-tolerant-networking",
        "evidenceBoundary": "NTRS provides open full text, but this conference paper was screened for curation rather than independently or domain reviewed; inclusion is contextual, not automatic claim evidence."
      }
    },
    {
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      "recordId": "ntrs-20240007189",
      "title": "The Space Superhighway: Enabling Active Debris Remediation Through an In-Space Logistics Infrastructure ",
      "publicPath": "/atlas/ntrs-20240007189",
      "recordFingerprint": "a75db6d94899d3232f317ea167c2a9d7962a9d7974ae0c04030bf7386920a17b",
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      "snapshot": {
        "id": "ntrs-20240007189",
        "title": "The Space Superhighway: Enabling Active Debris Remediation Through an In-Space Logistics Infrastructure ",
        "url": "https://ntrs.nasa.gov/citations/20240007189",
        "topic": "assembly-logistics",
        "year": 2024,
        "publishedAt": "2024-08-08T04:00:00.0000000+00:00",
        "authors": [
          "John W. Mulvaney",
          "Dale C. Arney",
          "Benjamin A. Merrel",
          "Daniel J. Tiffin"
        ],
        "publisher": "Langley Research Center",
        "resourceType": "Conference Paper",
        "access": "open full text",
        "abstract": "The Space Superhighway is a future space infrastructure concept intended to support civil, commercial, and national security space interests by providing In-Space Servicing, Assembly, and Manufacturing (ISAM) services across low Earth orbit (LEO), geosynchronous orbit (GEO), and cislunar space. This concept was originally developed by an interagency working group and commissioned by the Executive Office of the President. The Space Superhighway is comprised of three primary components: regional hubs, a sustainable transportation network, and Earth-to-orbit logistics. This study establishes methods which may be used to quantify the cost-savings from use of the Space Superhighway infrastructure and interrogates the effects of the use of this logistics network on a specific use case – removal of 26 pieces of large space debris within LEO. Through application of the established methods and assuming an emplaced Space Superhighway infrastructure with no cost implications related to deployment of infrastructure-related spacecraft, this study found that the cost to use an established Space Superhighway infrastructure to remove the targeted debris may be cheaper than removal of the targeted debris through traditional methods when the ΔV between a regional hub hosting propellant and the debris field is less than 1500 m/s. Through determining optimized locations of regional hubs within LEO, this study estimates that such a ΔV is within expectations for a LEO environment supported by a fully evolved Space Superhighway logistics infrastructure. This study provides a blueprint for future Space Superhighway value proposition studies for other use cases which, when combined, may provide the ultimate benefit and justification for the proliferation of an interconnected Space Superhighway.",
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      "recordId": "ntrs-20240012115",
      "title": "Expanding Ketamine Application for Treatment of Acute Suicidality in Long-Duration Spaceflight",
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        "title": "Expanding Ketamine Application for Treatment of Acute Suicidality in Long-Duration Spaceflight",
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        "topic": "health-medicine",
        "year": 2024,
        "publishedAt": "2024-10-25T05:00:00.0000000+00:00",
        "authors": [
          "Craig J Kutz",
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        "abstract": "Introduction. The transition to exploration missions places a heightened risk on behavioral health in spaceflight. Although serious psychiatric emergencies during spaceflight have been rare, longer duration missions increase the possibility of emergence in latent mental health disorders due to genetic predisposition, increased autonomy, isolation, helplessness, loss of family member, or catastrophic events. Complicated grief and bereavement have the highest rate of suicidal ideation.  Recently, ketamine has been used as an emergent intervention for acute suicidality, promoting its stability, ease of administration, favorable safety profile, and outcomes for reduction of suicidal intent. The goal of this study was to review current literature and collate the understanding of ketamine as a safe, effective pharmacological adjunct for acute suicidality in spaceflight. \n\nMethods. This literature review was conducted to collate data on ketamine use for acute suicidality and inform on stability, limitations and utilization of ketamine within extreme environments.\n\nResults. 122 publications were reviewed for relevance including 23 randomized-control trials for ketamine use in behavioral emergencies.  \n\nDiscussion. Ketamine is a diverse pharmaceutical with multiple advantageous indications, including acute suicidality, pain, and sedation. Terrestrial use of ketamine suggests a rapidly efficacious medication for reduction in acute suicidality.  As behavioral stressors expand related to extended missions, contingencies for behavioral emergencies become increasingly important. Although this review is not intended to re-develop current International Space Station (ISS) protocols, it is the first to discuss the benefits of ketamine in spaceflight as a potential safe, effective multifaceted tool for future exploration missions and treatment for acute suicidal ideation.",
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        "authors": [
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