# GShips offline review-notes worksheet Status: blank notes companion; not a decision bundle Packet: `systems:health-medicine` Packet SHA-256: `53fc3a32e94120c4f258f2416b6d03c3bec4fe608b16b842b1af5565f37ad61e` Release: `public-alpha-2026-07-26-research-visuals-r14` Source commit: `3eb036fce3d711336c8c605625895e8a2e799ab0` This readable worksheet is for local notes only. It cannot satisfy the closed decision-bundle schema and is not input to the validator. Use the fingerprinted JSON template for any future structured decision. This worksheet appoints nobody and records no completed review. Do not put identity documents, private contact data, medical or accessibility records, confidential conflict evidence, controlled material, or exploit details here. Keep notes offline until a separately authorized private handoff exists. ## Reviewer declaration Opaque public reviewer ID: Public label: Controlled scope codes: Qualification basis: Independence status and bounded basis: Conflict public summary: Compensation status and public summary: AI assistance and human-verification statement: Publication consent selections: ## 1. Medicine, public health & human performance - Record: `system:health-medicine` - Record SHA-256: `c5a0a79dc6997542128ab5531efc2d19b0c825fd0b3d972a5d42bb0faa49ccb3` - Public record: /systems/health-medicine - Minimum independent approvals: 1 - Required scope groups: bounded-competence (clinical-health, human-factors) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 2. Medicine aboard a generation ship is a complete public-health system across conception, childhood, adulthood, aging, disability, emergency care, and death. - Record: `claim:claim-07-01` - Record SHA-256: `16edaf55cf586b029299f809f1da1fd9dbd309bb605915709f28f9c96f986302` - Public record: /claims/claim-07-01 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 3. Evidence from small, highly selected adult occupational cohorts—mostly in low Earth orbit—identifies risks involving radiation, bone, muscle, vision, sleep, behavior, and immune function but does not establish lifetime outcomes for a diverse civil population. - Record: `claim:claim-07-02` - Record SHA-256: `f47c71baed23d310648bb7432627c2f162e25f5091193a459317059796cee19b` - Public record: /claims/claim-07-02 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 4. Remote clinical decision support, tissue models, omics, analogs, and commercial-astronaut repositories are active research areas. - Record: `claim:claim-07-03` - Record SHA-256: `ecd6abbda99c1b715eff563892a7523ec37a44099f6a1f55ab978551fb3ec6c5` - Public record: /claims/claim-07-03 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 5. This bounded review found no published evidence of a human pregnancy carried through birth, or of childhood development, in an off-Earth environment. - Record: `claim:claim-07-04` - Record SHA-256: `45f3421a9c005b76bf080010573b171ee0f1f13ab612c512112101a80aea0833` - Public record: /claims/claim-07-04 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 6. Animal, cellular, and adult-flight studies provide bounded precursor evidence, but do not establish human pregnancy, placental function, birth, pediatric development, lifetime fertility, or transgenerational outcomes in altered gravity. - Record: `claim:claim-07-05` - Record SHA-256: `b6c2c7319a2c423259885f958c14e4d678e2a3fb7ee750e021935214b2e246b3` - Public record: /claims/claim-07-05 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 7. Pharmaceutical manufacture, shelf life, surgery, dentistry, intensive care, and rare-disease management lack independent support chains. - Record: `claim:claim-07-06` - Record SHA-256: `982f06d58f7ade56755e58b28c7a0dc78f29b9c07e6aeb4aa2449b4e9f8b2aff` - Public record: /claims/claim-07-06 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 8. Clinical privacy and authority may conflict with mission command, population planning, and public-health surveillance. - Record: `claim:claim-07-07` - Record SHA-256: `da48c0ccc0047cefeab0639bf42a95c5baf564b8012e5eb555fe883d1da58971` - Public record: /claims/claim-07-07 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, governance-law-rights, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 9. Bounded, prospectively validated clinical decision support and resilient medical supply may benefit rural care, maritime operations, disaster medicine, and aging populations; local monitoring, abstention, provenance, appeal, and an AI-off care path remain required. - Record: `claim:claim-07-08` - Record SHA-256: `05d5483fd7855199481f47edf9d0e118292e435f95ff9011f63816f5a8363014` - Public record: /claims/claim-07-08 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, defensive-cyber-safety, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 10. Closed-habitat environmental and clinical surveillance may inform infection control in named shared-air or shared-water settings when sampling, thresholds, confirmation, privacy, and interventions are validated; improved health outcomes are not established generically. - Record: `claim:claim-07-09` - Record SHA-256: `eb07a909159bf8bc412062a325d78164d3c85c86b18790ff131f123a9a9f0e68` - Public record: /claims/claim-07-09 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, governance-law-rights, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 11. Do not rely on reproduction until independent evidence supports the intended environment and the architecture remains viable under voluntary reproductive choices, accessible clinical care, privacy, appeal, disability support, and no coercive quotas. - Record: `claim:claim-07-10` - Record SHA-256: `4d7bd9dd625436463cf5268ec1d0820e74c3173da6aed67a7b8674c78daf96b9` - Public record: /claims/claim-07-10 - Minimum independent approvals: 2 - Required scope groups: domain-method (clinical-health, governance-law-rights, human-factors); rights-public-interest (affected-public-rights) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 12. Recommendations for Environmental Infection Control in Health-Care Facilities - Record: `claim-source:src-ca-cdc-environmental-control` - Record SHA-256: `a05b130ce017d16a79ea68e18f42ad4f870925180057cf3d2be34990c77ae176` - Public record: https://www.cdc.gov/infection-control/hcp/environmental-control/recommendations.html - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 13. Supporting the Constellation of Reproductive Rights - Record: `claim-source:src-gr-unfpa-reproductive-rights` - Record SHA-256: `dd9c7fd4c4a780d784706fe50cc5e7181a0310656604ca504f81fb2d70eb839b` - Public record: https://www.unfpa.org/resources/supporting-constellation-reproductive-rights - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 14. Spaceflight Multi-Omics Reveals Vulnerabilities of Human Germ Cell Development - Record: `claim-source:src-hc-li-spaceflight-germ-cells-2026` - Record SHA-256: `088d8f9be6fdf15bfe2df7f39de9ab3a2e579994d780e2c9df5027e49fb85088` - Public record: https://doi.org/10.1126/sciadv.aee0143 - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 15. Simulated Microgravity Alters Sperm Navigation, Fertilization and Embryo Development in Mammals - Record: `claim-source:src-hc-lyons-simulated-microgravity-2026` - Record SHA-256: `e6bb3806105df3dc180ec2a6bae4996aa3979736f7edacfa1c8da82e1ee381ff` - Public record: https://doi.org/10.1038/s42003-026-09734-4 - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 16. Human Research Program Hazard: Gravity Fields - Record: `claim-source:src-hc-nasa-altered-gravity` - Record SHA-256: `a35ec30cfc1e26a87bedde685e46a23a2ff8ff43b31a8134bfe5f3374600b0ed` - Public record: https://www.nasa.gov/hrp/hazard-gravity-fields/ - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 17. Human Research Program - Record: `claim-source:src-hc-nasa-hrp` - Record SHA-256: `f6e1041fc2b0a784b7ddd3e02d429a9f5cfa7450e67fcf1fe2f62e456b8b208f` - Public record: https://www.nasa.gov/hrp/ - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 18. Effect of Microgravity on Mammalian Embryo Development Evaluated at the International Space Station - Record: `claim-source:src-hc-wakayama-iss-embryos-2023` - Record SHA-256: `ce524a1b4fef0d5a6645c2d176c41a5c4bf44c7e352eb9895c6d562d2443f9a7` - Public record: https://doi.org/10.1016/j.isci.2023.108177 - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 19. Evaluating the Long-Term Effect of Space Radiation on the Reproductive Normality of Mammalian Sperm Preserved on the International Space Station - Record: `claim-source:src-hc-wakayama-iss-sperm-radiation-2021` - Record SHA-256: `763d80ab38bc6ae9360de1c2fd5cfa6c4927a5db43609fd53ef20362744d8b88` - Public record: https://doi.org/10.1126/sciadv.abg5554 - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 20. Guidance for Managing Ethical Issues in Infectious Disease Outbreaks - Record: `claim-source:src-hc-who-emergency-ethics` - Record SHA-256: `7e046f25df3e370c116fc724e608a98f541ff777a39f07df9b62762e8d479b97` - Public record: https://www.who.int/publications/i/item/9789241549837 - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 21. International Health Regulations - Record: `claim-source:src-hc-who-ihr` - Record SHA-256: `aef99344f225f5ad406385185d575ae617833961eff50b0947eb2c598d791b0b` - Public record: https://www.who.int/health-topics/international-health-regulations - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 22. Clinical Decision Support Software: Guidance for Industry and Food and Drug Administration Staff - Record: `claim-source:src-pa-fda-cds-2026` - Record SHA-256: `7762e93039a1b4bdecef5b28f15006618e0a691680bac99138380839853217f5` - Public record: https://www.fda.gov/regulatory-information/search-fda-guidance-documents/clinical-decision-support-software - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: ## 23. Artificial Intelligence Risk Management Framework: Generative Artificial Intelligence Profile - Record: `claim-source:src-pa-nist-ai-600-1` - Record SHA-256: `4066eeecafdc810d0ad828dd8bd53e4a05daeb6b03dde36fafe581976402cb59` - Public record: https://doi.org/10.6028/NIST.AI.600-1 - Minimum independent approvals: 1 - Required scope groups: bounded-competence (information-science) Disposition: [ ] approve [ ] revise [ ] contest [ ] reject [ ] recuse Bounded scope: Rationale: Evidence source ID, exact locator, and finding: Proposed correction or recusal reason: What would change this decision: