Immune responses in humans after 60 days of confinement
A confinement experiment in a normobaric diving chamber was undertaken to better understand the effect of confinement and isolation on human psychology and physiology. Pre- and postconfinement blood samples were obtained from four test subjects and control donors to analyze immun
Selection note: Curated because this 1995 reprint (version printed in journal) from Legacy CDMS specifically covers “Immune responses in humans after 60 days of confinement”; its abstract describes A confinement experiment in a normobaric diving chamber was undertaken to better understand the effect of confinement and isolation on human psychology and physiology. Pre-… This materially informs GShips human factors and habitability.
Evidence boundary: Only NTRS metadata and abstract are open here; full-text methods and results were unavailable for this pass. Inclusion is contextual discovery support, not automatic evidence for a GShips claim.
Stable record
ntrs-20050000230
Topic
human-factors
Type
Reprint (Version printed in journal)
Publisher
Legacy CDMS
Authors
Schmitt, D. A.; Peres, C.; Sonnenfeld, G.; Tkackzuk, J.; Arquier, M.; Mauco, G.; Ohayon, E.
Year
1995
Editorial state
metadata curated editorial draft
Reviewer
GShips Project editorial synthesis
Official link checked
2026-07-25
Source-supplied abstract
A confinement experiment in a normobaric diving chamber was undertaken to better understand the effect of confinement and isolation on human psychology and physiology. Pre- and postconfinement blood samples were obtained from four test subjects and control donors to analyze immune responses. No modification in the levels of CD2+, CD3+, CD4+, CD8+, CD19+, and CD56+ cells was observed after confinement. Mitogen-induced T-lymphocyte proliferation and interleukin-2 receptor expression were not altered significantly. Whole blood interferon-alpha and gamma-induction and plasma cortisol levels were also unchanged, as was natural killer cell activity. These data suggest that in humans, no specific components of the immune response are affected by a 2-month isolation and confinement of a small group.
Abstract text has not been adopted as a GShips conclusion.
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Only NTRS metadata and abstract are open here; full-text methods and results were unavailable for this pass. Inclusion is contextual discovery support, not automatic evidence for a GShips claim.
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People, review, and conflicts
Prepared by
GShips Project
Editorial status
metadata-curated-editorial-draft
Editorial reviewer
GShips Project editorial synthesis
Last editorial review
No editorial-review date recorded
Independent review
pending
Independent reviewer
No independent reviewer assigned
Last independent review
No independent-review date exists
Last content edit
Not recorded separately
Official source or link verified
2026-07-25
Declared conflicts
The maintainer intends to explore a commercial venture based on some GShips work. No entity, outside funding, customer, sponsor, or indexed-organization relationship currently exists.