GeneLab: The NASA Systems Biology Platform for Space Omics Repository, Analysis and Visualization
The NASA GeneLab project capitalizes on multi-omic technologies to maximize the return on spaceflight experiments. To do this, GeneLab maintains a publicly accessible database (GLDS) that houses spaceflight and spaceflight relevant multi-omics dataand collaborates with NASA princ
Selection note: Curated for NASA GeneLab as an open-data and systems-biology platform connecting multi-omics datasets, analysis standards, and reproducible space-biology research.
Evidence boundary: The conference record describes the platform, but this pass did not audit data quality, pipeline reproducibility, repository coverage, or continued service. It is research-infrastructure context, not biological claim evidence.
Stable record
ntrs-20205000334
Topic
reproduction-genetics
Type
Conference Paper
Publisher
Ames Research Center
Authors
Samrawit Getachew Gebre; Amanda Marie Saravia-Butler; Jonathan M Galazka; Sylvain Vincent Costes
Year
2020
Editorial state
metadata curated editorial draft
Reviewer
GShips Project editorial synthesis
Official link checked
2026-07-25
Source-supplied abstract
The NASA GeneLab project capitalizes on multi-omic technologies to maximize the return on spaceflight experiments. To do this, GeneLab maintains a publicly accessible database (GLDS) that houses spaceflight and spaceflight relevant multi-omics dataand collaborates with NASA principal investigators and projects to generate additional omics data. GeneLab houses more than 220 transcriptomic, proteomic, metabolomic and epigenomic datasets from plant, animal and microbial experiments, with a growing number of these having been produced by the GeneLab sample processing lab. The GLDS contains rich metadata about each experiment and has recently integrated radiation dosimetery data from experiments flown on the Space Shuttle. GeneLab has also recently implemented an effort to present processed data in the GLDS in addition to the raw omics data. The processed data will enable interpretationof the data by a larger group of students, scientists and the general public. Standard pipelines for the transformation of raw data into visualizations were developed by four GeneLab Analysis Working Groups (animals, plants, microbes, multi-omics) comprised of over 120 scientists from NASA, industry, and academia. To explore the data, the GLDS provides users various tools for data analysis, collaborative workspace for file storage and sharing, and a visualization portal. The analysis platform built using the Galaxy toolshed provides access to a broad variety of users including those with limited bioinformatics experience and students to learn how to analyze spaceflight omics data. The visualization portal takes GeneLab one step closer to data democratization by removing all bioinformatics requisites to interpret transcriptomics data hosted in the repository. Discoveries made using GeneLabhave begunand will continue to deepen our understanding of biology, advance the field of genomics, and help to discover cures for diseases, create better diagnostic tools, and ultimately allow astronauts to better withstand the rigors of long-duration spaceflight.
Abstract text has not been adopted as a GShips conclusion.
What would change this record?
A newer or corrected version, a retraction, a verified duplicate, a material topic mismatch, a changed access state, or claim-level review would trigger a dated editorial update.
The conference record describes the platform, but this pass did not audit data quality, pipeline reproducibility, repository coverage, or continued service. It is research-infrastructure context, not biological claim evidence.
Source-supplied titles, abstracts, authors, and dates may require correction against the canonical full text.
What would change this page?
A newer or corrected version, retraction, verified duplicate, material topic mismatch, changed access state, or claim-level assessment would change this record.
People, review, and conflicts
Prepared by
GShips Project
Editorial status
metadata-curated-editorial-draft
Editorial reviewer
GShips Project editorial synthesis
Last editorial review
No editorial-review date recorded
Independent review
pending
Independent reviewer
No independent reviewer assigned
Last independent review
No independent-review date exists
Last content edit
Not recorded separately
Official source or link verified
2026-07-25
Declared conflicts
The maintainer intends to explore a commercial venture based on some GShips work. No entity, outside funding, customer, sponsor, or indexed-organization relationship currently exists.