LEIA: An Investigation of Radiation Risks to Biology at the Lunar South Pole
Radiation and reduced gravity pose biological risks to crewed deep space exploration. At the cellular level, radiation damage can be amplified by reduced gravity. Empirical evidence on cellular responses to beyond low Earth orbit (BLEO) environments is imperative to develop effec
Selection note: Curated for the LEIA payload concept linking lunar-surface radiation measurements with biological responses in yeast, an Earth-orbit-to-lunar precursor for combined dosimetry and biology.
Evidence boundary: NTRS lists accessible presentation material, but this pass did not validate instrument performance, lunar exposure predictions, or biological inference. It is experiment-design context, not health-risk claim evidence.
Stable record
ntrs-20230016079
Topic
radiation-environment
Type
Presentation
Publisher
Ames Research Center
Authors
A Mark Settles; Natalie N Ball; Jared T Broddrick; Jessica W Chau; Bent Ehresmann; Diana M Gentry; Jennifer Gil Acevedo; Chinmayee Govinda Raj
Year
2023
Editorial state
metadata curated editorial draft
Reviewer
GShips Project editorial synthesis
Official link checked
2026-07-25
Source-supplied abstract
Radiation and reduced gravity pose biological risks to crewed deep space exploration. At the cellular level, radiation damage can be amplified by reduced gravity. Empirical evidence on cellular responses to beyond low Earth orbit (BLEO) environments is imperative to develop effective countermeasures for crew health and in-space biomanufacturing. The Lunar Explorer Instrument for Space Biology Applications (LEIA) project is developing an instrument suite to be delivered to the south polar region of the Moon by the Commercial Lunar Payload Services (CLPS) program. This presentation will provide an overview of the LEIA hardware, experiments, and mission timeline.
The LEIA instruments include the BioSensor, the ARES charged particle detector, and the Mini-FND. The BioSensor is an autonomous light emitting diode (LED)-based spectrophotometer and microfluidic incubator. The BioSensor activates yeast cultures and can measure cell growth, metabolic activity, and carotenoid production. The ARES is a Timepix-based charged particle radiation detector that measures dose, dose rate, and linear energy transfer spectra. The Mini-FND is a fast neutron detector that measures albedo neutron flux and energy spectra. Combined, these instruments will be used for yeast genetics experiments to quantify growth, metabolism, and synthetic biology-enabled production of human nutrients, while taking real time measurements of biologically relevant radiation exposure on the lunar surface. These data will be used to test the importance of selected DNA damage repair and reactive oxygen species defense pathways in mitigating cellular damage from lunar surface radiation.
Abstract text has not been adopted as a GShips conclusion.
What would change this record?
A newer or corrected version, a retraction, a verified duplicate, a material topic mismatch, a changed access state, or claim-level review would trigger a dated editorial update.
NTRS lists accessible presentation material, but this pass did not validate instrument performance, lunar exposure predictions, or biological inference. It is experiment-design context, not health-risk claim evidence.
Source-supplied titles, abstracts, authors, and dates may require correction against the canonical full text.
What would change this page?
A newer or corrected version, retraction, verified duplicate, material topic mismatch, changed access state, or claim-level assessment would change this record.
People, review, and conflicts
Prepared by
GShips Project
Editorial status
metadata-curated-editorial-draft
Editorial reviewer
GShips Project editorial synthesis
Last editorial review
No editorial-review date recorded
Independent review
pending
Independent reviewer
No independent reviewer assigned
Last independent review
No independent-review date exists
Last content edit
Not recorded separately
Official source or link verified
2026-07-25
Declared conflicts
The maintainer intends to explore a commercial venture based on some GShips work. No entity, outside funding, customer, sponsor, or indexed-organization relationship currently exists.